Welcome to the Kao Lab Website

The Kao lab seeks to understand the basic pathophysiological mechanisms underlying neurodegenerative diseases.

The goal of our research is to use C. elegans and patient-derived induced pluripotent stem cells (iPSCs) to better understand and ultimately cure neurodegenerative disease.  We focus on progranulin, tau and other newly discovered disease-associated genes in the regulation of cellular stress responses, protein homeostasis, pH dynamics and other processes. ​We strive to make the laboratory environment one that is based on excellence, a team-oriented approach and one that seeks out innovations, collaborations and change.